this is going to depend on what bike exactly. The older VT's have a high fatality ate at around 50,000km, due to running the big end bearing. Ive seen and ridden myself, quite a few cbr 250s that have done well over 100,000km, and are still going strong, and pulling hard.
Best option is to give us some examples of the bikes you are looking at, and ask for advice on the specific bikes you are interested in. And remember, dont just take the first couple answers as gospel, every bike has its haters, even though it may be an awesome bike. good luck and happy hunting!
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