have you heard of the series of case studies where they placed a cannula into the brain of people with endstage GBM (advanced brain cancer)? By means of that they put pretty hefty doses of cannabis directly into their tumours. The tumours regressed (shrank) for a period of time. The patients were high as.....clearly.... and did eventually die sadly. Not sure if the people who did that ever followed up on it. Point is that article makes reference to lots of animal model work but trials in people have happened too.
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