Agree with Drew. No comparison between the human body and a mechanical device in this context.
Giving a bike a good hard run may or may not improve it. Depends on the bike.
A highly tuned 2 stroke used in commuter mode will foul and clog. A good hard run should clear that. It's not designed to run in stop/start low rev mode.
A mild 4 stroke is designed to tug all day across a wide range of riding conditions. It won't complain too much, but a good thrashing occasionally will clear its lungs.
The cobwebs are a whole bunch of stuff like the engine mapping in your electronic gubbins if you have them ( coz some of them "learn" your riding style ), the carbon build up in your head and plugs, the various mechanical tolerances of 250 hot whizzy bits of metal, your own mental state on a a Sunday morning when you head out for a thrape with the lads.
It's a piece of machinery. Learn to get to know how it responds to external influences and keep it maintained. It'll let you know when it's unhappy.
...and that's why these guys talk about thrashing Jags to improve the state of tune. They were an expensive high performance car used as cruisers. A 20 minute squirt up the motor way gets them back in the comfort zone they were built for.
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