Basically, no. But there are differences in the additive packs, since cars don't have wet clutches like most bikes, and some of the additive packs added to car oil contain things that could cause wet clutches to slip. Also, your average bike engine revs higher than a car, and may have less oil in the sump (although mine doesn't) so allowances are made for that.
Many bike riders swear by decent diesel oils, as they're generally cheaper and made to some quite exacting standards.
I've tried all sorts of oils, and the only thing I've noticed is that some oils make the gear changes a little notchier. Mobil 1 (or 4T, or whatever it's called) is one of those. I've used it only once, and that was when it was on sale at AMPS for not much more than Motul 5100.
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